The organisation that became Primary Care Commissioning (PCC) started in the National Primary and Care Trust Development Programme (NatPaCT), designed to help newly formed primary care trusts to share intelligence, which later became part of the Modernisation Agency.  In 2006, several NatPaCT personnel started a new organisation NHS Primary Care Contracting, an NHS-hosted but self-funding organisation providing PCT primary care teams with advice, training and expert support.
NHS Primary Care Contracting played a leading part in the introduction of the new national primary care contracts and went on to provide annual subscription services to PCTs and strategic health authorities (SHAs) until their abolition in 2013.  
In 2009, the organisation secured its independence and set up as a social enterprise, Primary Care Commissioning Community Interest Company.
PCC continues to develop and manage NHS Networks, another initiative with roots in NatPaCT. Today NHS Networks provides a free collaboration, news and networking service to the NHS funded by PCC as part of our social mission.